The Galveston Railroad Museum is owned and operated by the Center for Transportation and Commerce. It was established with funds from Galveston businesswoman and philanthropist Mary Moody Northen and the Moody Foundation. The museum is headquartered in the old Gulf Colorado & Santa Fe depot building in Galveston, TX. The GC&SF was a Galveston based railroad that eventually linked with the Atchison, Topeka & Santa Fe and became the Texas subdivision of the Santa Fe.
By 1912, the AT&SF announced its plans to build a new
union depot in Galveston that would also house the offices of the Gulf, Colorado & Santa Fe. Their plans were for an eight-story fireproof building made of steel-reinforced concrete and faced with white enamelled brick. The waiting room would be 104 feet by 63 feet, and the building would be large enough to contain all of the departments of the GC&SF lines.
An addition to the building was made in 1932, which
included another eight-story building and an eleven-story tower. The company planned to spend $35,000 on this remodelling of the old building so that it would match the new structure.